Pathology EMQ template.

Name:

Candidate number:

Theme: Stem Cell Transplantation - Complications

 

OPTION LIST

 

A	Acute Graft vs. Host disease	I	Transfusion-associated Graft vs. Host disease
B	Candidiasis	J	Veno-occlusive disease
C	Chronic Graft vs. Host disease	K	VZV infection
D	CMV infection	L
E	Disease relapse	M
F	E.coli infection	N
G	Graft failure	O
H	Invasive aspergillosis	P

 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1.   A 6 year old boy with acute leukaemia is given an allogenic SCT from his brother. 8 weeks after the transplant, he develops severe diarrhoea and abdominal pain. On examination, a maculopapular rash is seen. What is the likely diagnosis?

 

2.   This is an early complication arising from HSCT characterized by fluid retention, hyperbilirubinaemia and hepatomegaly.

 

3.   Two months after a SCT, a 9 year old girl presents with a cough, fever and malaise. She also complains of diarrhoea and bloating.

 

4.   This life-threatening complication of SCT is characterised by a pancytopenia, giving rise to infections, anaemia and bleeding.

 

5.   Having been on long-term immunosuppression following an SCT, a patient presents with fever and malaise. He complained of some pain and a rash on a small patch of skin on the right side of his torso.

 

ANSWERS

1. A

2. J

3. D

4. G

5. K